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Every cell type has the capability of giving rise to cancer and, in general, the greater tbe replicative activity, the greater the cancer risk. However, there is neitber report on the extent of each cellular type of human body classified by cellular replicative activity, nor attempt to classify human malignant tumor by replicative activity of tissue of origin. The author tried to divide human body by 3 types of cell, so called, labile, stable and permanent cell, and calculated their percentage based on Forbes data on the gross composition of tbe adult body. And 1074 cases of malignant tumors diagnosed during 1976 1979 at Korea University Hospital were classified into labile, stable and permanent cell origin cancer based on replicative actvity of their tissue of origin. The data obtained are as following. l. Among tbe total cellular weight of adult human body, labile cells accounted for about 26%, and malignant tumors originated from this part occupied 83. 80% (900cases) of total 1074 cases. 2. Extent of stable cells in adult human body was about 14%, and percentage of malignant tumor from this part was 14.80%(159cases). 3. About 60% of adult human body was composed of permanant cells, but only 0. 37% (4cases) of malignant tumors were originated from this part. Above findings support the general knowledge.that the greater the replicative activity, the greater the cancer risk.
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